People often describe horses as having a “big heart” or a “strong spirit,” but what do these phrases actually mean from a scientific standpoint? While these expressions may feel meaningful to us, they often lead to anthropomorphic assumptions that don’t align with equine neurobiology. A horse’s behavior is shaped by its nervous system, past experiences, and immediate environment—not by human concepts of bravery or kindness. Understanding the neurochemical drivers behind motivation, stress responses, and social bonding helps us interpret horse behavior more accurately. Instead of relying on labels, we can recognize horses for what they truly are—highly adaptive prey animals that thrive on consistency, clear communication, and a sense of safety.